Rheumatology

Sjögren's Disease

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Looking Ahead to ACR Convergence 2026: The Topics Our Experts Are Excited About

conference reporter by Thomas Grader-Beck, MD, PhD; R. Hal Scofield, MD
Overview

As the Sjögren’s Disease community prepares to gather for ACR Convergence 2026, anticipation is building around the latest developments in treatment, diagnostics, clinical research, and patient care. Ahead of this year’s meeting, we asked our Expert panel to share what they are most eager to follow and the developments they believe could have the greatest impact.

"What I am most excited to follow at ACR Convergence 2026 is how advances in therapeutics, imaging, and biomarkers are beginning to reshape the way we think about Sjögren’s disease. With multiple targeted therapies showing efficacy in clinical trials, the next challenge is to understand which disease manifestations and patient subsets are most likely to respond to a given mechanism of action. I am particularly interested in whether these drugs may improve glandular function and have a positive effect on fatigue, one of the most debilitating symptoms of Sjögren’s disease. Additionally, salivary gland ultrasound and emerging biomarkers may help characterize endotypes and disease activity, respectively, and may identify treatment-responsive populations. Ultimately, these advances may help us move beyond treating Sjögren’s as a single disease and toward a more individualized approach to therapy."
— Thomas Grader-Beck, MD, PhD
“At ACR Convergence 2026, I am looking forward to the presentations on new clinical trial data for Sjögren’s disease. Historically, treatment for Sjögren’s disease has mostly been symptomatic, but we now have multiple targeted therapies in phase 3 trials. I will be looking out for the overall efficacy data, as well as the data on which patients are most likely to benefit from each therapy. In addition, I anticipate that new data will be shared on repurposing already available medications for Sjögren’s disease. Lastly, I will be on the lookout for presentations that share new insights on the pathophysiology of Sjögren’s disease, as these will surely give rise to new therapeutic targets."
— R. Hal Scofield, MD

Stay tuned for continued coverage from ACR Convergence 2026, where our Conference Reporter Expert panel will share key takeaways, emerging data, and expert perspectives throughout the meeting as part of our Conference Reporter® in Sjögren’s Disease series.

 

This information is brought to you by Engage Health Media and is not sponsored, endorsed, or accredited by the American College of Rheumatology.

Thomas Grader-Beck, MD, PhD

Associate Clinical Professor of Medicine
Division of Rheumatology
Johns Hopkins University School of Medicine
Baltimore, MD

R. Hal Scofield, MD

Professor, Arthritis & Clinical Immunology Research Program
Oklahoma Medical Research Foundation
Professor, Department of Internal Medicine
Adjunct Professor, Department of Pathology
The University of Oklahoma Health Sciences Center
Associate Chief of Staff for Research
Oklahoma City US Department of Veterans Affairs Medical Center
Oklahoma City, OK

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