Nephrology
Renal Transplant Maintenance
Patient Care Perspectives Podcast: Educating Patients and Clinicians on the Future of Kidney Transplantation
Kidney transplantation can transform quality of life, but long-term maintenance therapy still requires clinicians to balance effective immunosuppression against toxicity, graft function, rejection risk, and patient burden. In today’s podcast, Flavio G. Vincenti, MD, discusses the current role of calcineurin inhibitors, the evolving roles of belatacept and other biologic strategies, and the importance of measured patient education about emerging technologies such as xenotransplantation and bioartificial kidneys.
Chandran S, Vincenti F. Antiplasma cell antibodies: a new era of human leukocyte antigen antibody control in solid organ transplantation. Am J Transplant. 2025;25(1):19-26. doi:10.1016/j.ajt.2024.10.005
Crannell WC, Perkins JD, Leca N, Kling CE. Deceased donor kidneys are discarded at higher rates when labeled as high kidney donor profile index. Am J Transplant. 2022;22(12):3087-3092. doi:10.1111/ajt.17197
Kawai T, Williams WW, Elias N, et al. Xenotransplantation of a porcine kidney for end-stage kidney disease. N Engl J Med. 2025;392(19):1933-1940. doi:10.1056/NEJMoa2412747
Vincenti F, Shoji J, Wojciechowski D, et al. Dual costimulation blockade with the CD154-specific fusion protein dazodalibep and belatacept for prophylaxis of kidney allograft rejection. Am J Transplant. 2026;26(4):797-806. doi:10.1016/j.ajt.2025.12.290
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